Program

Fall Workshop Program

The workshop program will take place at the Hyatt Regency Boston Harbor Hotel
101 Harborside Drive
Boston, Massachusetts
Telephone is (617) 568-1234
THURSDAY, NOVEMBER 2
7:30 - 8:15 am
Registration check in

Session 1: 8:30 - 10:10 (includes discussion)
  • Introduction to top-down mass spectrometry: Joseph Loo, UCLA 
  • Instrumentation for top-down mass spectrometry: Ron Heeren, Maastricht University
10:10 - 10:30 Break

Session 2: 10:30 - 12:10 (includes discussion)
  • Sample preparation for top-down mass spectrometry: Jeff Agar, Northeastern University
  • Chromatographic separation strategies for top-down proteomics: Ying Ge, UW-Madison
12:10 - 1:30: Group Lunch

Session 3: 1:30 - 3:10 (includes discussion)
  • Tandem mass spectrometry techniques for top-down proteomics: Jennifer Brodbelt, UT-Austin
  • Quantitative strategies in top-down proteomics: Neil Kelleher, Northwestern University
3:10 - 3:30 Break

Session 4: 3:30 - 5:10 (includes discussion) 
  • How to interpret top-down high-resolution mass spectrometry data: Ying Ge, UW-Madison
  • Bioinformatics for top-down proteomics: an overview Ljiljana Paša-Tolić, PNNL
5:10 - 6:30: Happy Hour / Networking
6:30: Dinner (on your own)

FRIDAY, NOVEMBER 3
8:00 - 8:30 am: Continental Breakfast

Session 5: 8:30 - 10:10 (includes discussion)
  • Top-down mass spectrometry analysis of post-translational modifications: Case studies Cathy Costello, Boston University 
  • Top-down imaging mass spectrometry: Ron Heeren, Maastricht University
10:10-10:30 Break

Session 6: 10:30 - 12:10 (includes discussion)
  • Top-down proteomics applications in human disease: Jeff Agar, Northeastern University
  • Top-down proteomics application in pharmaceutical industry: Jason Rouse, Pfizer, Inc.
12:10-1:30: Group Lunch

Session 7: 1:30 - 3:10 (includes discussion) 
  • Top-down proteomics applications in microbiology: Ljiljana Paša-Tolić, PNNL
  • Top-down LC/MS strategies in analysis of antibody-drug conjugate (ADC): Leiza Dana-Leon, Abbvie Stemcentrx
3:10-3:30 Break

Session 8: 3:30 - 5:10 (includes discussion) 
  • Native top-down proteomics of protein complexes: Joseph Loo, UCLA
  • The future of top-down proteomics: Neil Kelleher, Northwestern University
Closing remarks: 5:10 - 5:20