Concept 7: Quantification via IDMS

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Further Information


Objective

Introduction

Statement of the Problem

Solutions

Approach (Methods)

Concept 1: Mass Spectrometer

Concept 2: How is it used

Concept 3: Mass Analysis

Concept 4: Ions and Charge

Concept 5: Ionization Techniques

Concept 6: Tandem MS

Concept 7: Quantification via IDMS

Concept 8: Accuracy and Precision

Summary

Concept 7: Quantification via IDMS

Simple Definition: It is a method that measures how much compound X is present in a liquid, solid or gas. This method uses non-radioactive elements called stable isotopes to make a comparison of compound X with the standard that contains the stable isotope. Since the amount of stable isotope standard is known we can calculate how much compound X is present.
Jelly Bean Analogy
How many Cherry Jelly Beans are in the jar?	How much phenylalanine is present in Blood
1. Add a marker or standard

Obtain a sample.

3. Analysis.

3. Calculations

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