Concept 5: Ionization Techniques

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Further Information


Objective

Introduction

Statement of the Problem

Solutions

Approach (Methods)

Concept 1: Mass Spectrometer

Concept 2: How is it used

Concept 3: Mass Analysis

Concept 4: Ions and Charge

Concept 5: Ionization Techniques

Concept 6: Tandem MS

Concept 7: Quantification via IDMS

Concept 8: Accuracy and Precision

Summary

Concept 5: Ionization Techniques

¹Mass Spectrometrist Definitions:
	Electrospray: formation of charged liquid droplets from which ions are desolvated or desorbed.	MALDI: (matrix assisted laser desorption ionization.) impact of high energy photons on a sample imbedded in a solid organic matrix.
Layperson Understanding: None. How does this relate to weighing molecules?
Simple Definition: Ionization is a process of charging a molecule. Molecules must be charged in order to measure them using a mass spectrometer. "It makes a molecule fly in a mass spectrometer."
Electrospray		MALDI

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