Mass Spectrometry Technologies for Structural Biology
Final Program
After over half a century of research in structural biology, it is now apparent that no one tool will be able to provide structural information for the entire compliment of biomolecules that play critical biochemical roles. Instead, data from multiple techniques are being integrated to solve previously intractable problems. Mass spectrometry is already playing a central role in this new revolution in structural biology, due to its ability to analyze complex mixtures, its high information content, and its low limits of detection. In addition, technologies closely related to mass spectrometry: ion mobility spectrometry, ion spectroscopy, chemical labeling, and H/D exchange are becoming common-place approaches to a host of challenging areas in biomolecular structural characterization.
This conference seeks to bring together a wide array of experts that have already contributed substantially to the impact of mass spectrometry in structural biology, and seeks to aid the development of mass spectrometry-based technologies specifically within the context of new integrative structural biology approaches. The timeliness of this conference coincides with the rapidly expanding role of mass spectrometry in structural biology, which is presently not coherently addressed by the arranged symposia at the Annual ASMS Conference. We envision a dedicated conference, that integrates presentations on the various mass spectrometry technologies and approaches, would be very well received both by current practitioners in the field and also, and potentially more importantly, by an audience comprised of structural biologists that do not presently appreciate the recent and rapid advances that mass spectrometry has made in this field.
Preliminary Program
Thursday, January 19
7:00 - 7:10 pm Opening Remarks
7:10 - 8:10 pm Plenary Lecture
Carol V. Robinson, University of Oxford
8:10 - 10:00 pm Welcome Reception
Friday, January 20
8:30 - 11:20 am Session 1: Structural Characterization by Ion Mobility
Julie Leary, UC Davis
David E. Clemmer, Indiana University
Joseph A. Loo, UCLA
Albert J.R. Heck, Utrecht University
Brandon T. Ruotolo, University of Michigan
11:40 am - 12:40 pm Session 2a: Structural Characterization by
Ion Activation/Fragmentation
Justin L.P. Benesch, University of Oxford
Vicki H. Wysocki, University of Arizona
12:40 - 2:00 pm Group Lunch
2:00 - 3:30 pm Session 2b: Structural Characterization by Ion Activation/Fragmentation
John S. Klassen, University of Alberta
Nick Polfer, University of Florida
Evan R. Williams, UC Berkeley
3:30 - 7:00 pm Free time and Dinner, on your own
7:00 - 8:00 pm Promoted Poster Session 1, four 15-minute poster talks
8:00 - 10:00 pm Poster Session 1
Saturday, January 21
8:30 - 10:30 am Session 3: Structural Characterization by Hydrogen/Deuterium Exchange
John R. Engen, Northeastern University
Michael C. Fitzgerald, Duke University
Igor A. Kaltashov, University of Massachusetts
Alan G. Marshall, Florida State University and National High
Magnetic Field Laboratory
11:00 am - 1:00 pm Session 4: Labeling Strategies for Structural Characterization
Lars Konermann, University of Western Ontario
Mark Chance, Case Western Reserve
Ryan Julian, UC Riverside
1:00 - 7:00 pm Lunch & Dinner, on your own
7:00 - 8:00 pm Promoted Poster Session 2, four 15-minute poster talks
8:00 - 10:00 pm Poster Session 2
Sunday, January 22
9:00 - 11:15 am Session 5: Emerging Directions and Techniques
David H. Russell, Texas A&M University
Scott McLuckey, Purdue University
Richard D. Smith, Pacific Northwest National Laboratory
John A. McLean, Vanderbilt University
11:30 am - 12:30 Closing Plenary Lecture
Brian T. Chait, Rockefeller University
12:30 - 12:45 pm Closing Remarks