Protein Therapeutics

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	Analytical Laboratory Managers

	Bioinformatics for MS

	Clinical Chemistry

	DNA/RNA

	Drug Meta. and Pharmacokinetics

	Energy, Petroleum and Biofuels

	Environmental Applications

	Flavor, Fragrance and Foodstuff

	Forensics and Homeland Protection

	FTMS

	Fundamentals

	H/D Exchange and Covalent Labeling

	Imaging MS

	Ion Mobility MS

	Ion Trap Mass Spectrometry

	LC/MS & Related Topics

	Metabolomics

	Metal Ion Coordination Chemistry

	Peptide Fragmentation

	Pharmaceuticals

	Polymeric Materials

	Protein Therapeutics

	Quantitative Intact Proteomics

	Regulated Bioanalysis

	Undergrad Research in MS

	Young Mass Spectrometrists

Protein Therapeutics

Group Coordinators: Jon Williams, (GlaxoSmithKline) and Sheng Gu, (Biogen)

Coordinator contact

This group is concerned with characterization of protein therapeutics by mass spectrometry, one of rapidly growing fields in the biopharmaceutical industry. Structural aspects of protein therapeutics include chemical modifications, post-translational modifications and conformational dynamics. Quantitative analysis covers MS assay of protein therapeutics (in vivo) and assessment of relative levels of modifications.

History of PTIG (Coordinator)

2009-2011 Guodong Chen (Bristol-Myers Squibb)

2010-2012 Jon Williams (GlaxoSmithKline)

2011-2013 Sheng Gu (Biogen)

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